October 10th, 2009 | by menopause-expert |
2,250,000 menopause women concerns in Belgium and France in 10,200,000.
The therapies hormone replacement was a great leap in medical care for women and the sign of a change of mentality. Finally, medicine no longer regarded as self-evident disorders including women complained it was no longer a simple matter of convenience. Today, 25% to 30% of postmenopausal women are using hormone replacement therapy. But did all women should provided it? What is acting hormones in hormone replacement therapy?
Cardiovascular risks
The causes of death among women over 50 years are:
- Cardiovascular disease: 53%
- ****** cancer: 4%
- Other cancers: 18%
- Accidents and suicides: 2%
Women who are more educated have a level of good cholesterol – HDL – high. Stress coupled with lack of social integration and contact with friends in the disadvantaged social classes is an important factor in coronary disease.
The vascular system
The hormones undoubtedly have a beneficial effect on the endothelium of the vessel wall. Indeed, menopause usually occur a decrease in resistance and plasticity of the uterine arteries and vasodilatation, thus widening of the aorta and coronary arteries.
The hormones (especially progesterone) also act on the lipoprotein and thus atheroma (fatty degeneration of the interior of the artery). They have an effect on homodynamic factors: during a hot flash are released large amounts of adrenaline and nor epinephrine, the same neurotransmitters as stress and sexual excitement, the adrenaline rises and the noradrenalin decreases, which leads to peripheral vasodilatation and vasoconstriction Central. That is why a burst of heat accompanied by flushing (vasodilatation). Finally, estrogen prevent too much calcium can flow toward the vascular wall.
Hormones and osteoporosis
The hormone replacement therapy acts primarily by the hormones estrogen, on cells forming bone ( osteoblasts). It is effective to prevent bone decalcification (without filling the backlog). However, the hormone needed is similar to those of young women during menstruation, which is not without running a risk of abnormal transformation. But it is true that, against all odds, there is a very small percentage (1.2%) patients who have post menopausal, when they take hormones, lose more than 1% of bone mass by year.
There is a major of hormone replacement therapy risks association with a low socio-professional category. The level of education has a role to play, since it, women who have not been studies that have poorer health compared to those graduates.
